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Ganoderma General |
Articles about Ganoderma - 3Effect of Ganoderma on drug-sensitive and multidrug-resistant small-cell lung carcinoma cellsMultidrug resistance is a major problem in small-cell lung cancer (SCLC). Ganoderma lucidum is a widely used herb in traditional Chinese medicine. We tested the effects of Ganoderma on drug-sensitive (H69) and multi-drug resistant (VPA) human SCLC cells. Both cells showed equal cytotoxicity when incubated with extracts of mycelia of 9 species of Ganoderma, including G. lucidum. Cells treated with the IC(50) of cytotoxic Ganoderma and analyzed by flow cytometry-PI staining showed increases in S phase. When compared untreated controls or SCLC cells treated with extracts of non-cytotoxic Ganoderma species, cells treated with extracts of cytotoxic Ganoderma species responded with an induction of apoptosis similar to cells treated with the chemotherapeutic drugs etoposide and doxorubicin ... ... continue
What is Ganoderma Lucidum?
To find lingzhi in ancient times, people had to go high up to the mountains and deep into the forest to harvest this most valuable medicine. It is rarely found since it flourishes mainly on the dried trunks of dead plum, guercus serrata or pasonia trees. Out of 10,000 such aged trees, perhaps 2 or 3 will have ganoderma growth. Ganoderma has more than 200 active elements which can be divided into three categories: water soluble elements; organic soluble elements; and volatile elements. The main elements are Polysaccharide, Organic Germanium, Adenosine, Triterpenoid and Ganoderic Essence. Proteins, amino acids, fibers, enzymes, vitamins and minerals can be found in Ganoderma as well. ... continue Ganoderma - The Health Benefits of GanodermaMore commonly known as reishi, ganoderma is a hard, bitter mushroom used to promote health and longevity in traditional Chinese medicine. Proponents claim that ganoderma can relieve fatigue, keep cholesterol in check, curb high blood pressure, tame inflammation, build stamina, and support the immune system. An increasingly popular natural remedy, ganoderma is only used as a medicinal mushroom and isn't recommended for cooking ... ... continue Know what you eatHowever, what are the foods that associates with alkaline and acid? Please refer to the diagram below to understand which food category represents alkaline and which food category represents acid ... ... continue
Comparative Studies of Delignification Caused by Ganoderma Species J. E. Adaskaveg, R. L. Gilbertson, and R. A. Blanchette Ganoderma meredithiae caused a simultaneous decay, with only small localized regions of cells delignified, while delignification by G. zonatum was irregular, with specific zones within the cell wall delignified. The thermophilic and chlamydosporic G. colossum has the capacity to cause extensive delignification and appears ideally suited for use in lignin degradation studies and biotechnological applications of lignin-degrading fungi. ... continue Ganoderma: Mushrooms for Your HealthMuch more than a friendly fungus to include in your cooking, mushrooms can offer health-boosting properties if you choose the right varieties. Cordyceps, for instance, might increase exercise endurance, while shiitake has long been used in traditional Chinese medicine to help stave off colds. To harness the healing properties of these medicinal mushrooms (which also include varieties like maitake and turkey tail), scientists have begun creating supplements that provide concentrated doses of their inflammation-fighting, antioxidant components. ... ... continue kona coffeeTrue kona coffee is grown only in the northern and southern parts of the mountainous kona region in hawaii Gano Café is aCombining the best Brazilian coffee beans and Ganoderma extract. No one knows exactly how they are able to extract the herb mainly on the secret of their success. There are some other companies are trying to replicate Gano Excel. They break, grind and mash up the value of red mushrooms, affect the appearance and taste of the product. Without using the right way to extract the nutrients that other companies could never be the results found may be similar toGanoCafé ... ... continue A novel three-stage light irradiation strategy in the submerged fermentation of medicinal mushroom Ganoderma lucidum for the efficient production of ganoderic acid and Ganoderma polysaccharidesA novel three-stage light irradiation strategy in the submerged fermentation of medicinal mushroom Ganoderma lucidum for the efficient production of bioactive metabolites ganoderic acid (GA) and Ganoderma polysaccharides was developed. Significance of light quality, i.e., blue light (390-500 nm, lambda(max) = 470 nm), red light (560-700 nm, lambda(max) = 625 nm), and white light (400-740 nm, lambda(max) = 550 nm), was studied at first. Interestingly, there was a gradual decrease trend of GA content after the culture of day 2 when the maximal GA content was obtained, while GA content decreased slowly under white light irradiation after day 6 ... This is the first report investigating the significance of light irradiation on the medicinal mushroom submerged fermentation. Such work is very helpful to other mushroom fermentations for useful metabolite production ... continue Ganoderma CoffeeGanoderma coffee has arrived in a big way to rejuvenate the health and life of avid coffee loving Americans! Most of you are aware of the ill effects of excess caffeine consumption. So when you are sipping into a cup of Ganoderma coffee you can rest assured that your health is totally safe guarded! This marvelous herbal concoction of coffee and Ganoderma has become immensely popular globally. The origin of this amazing fungus can be traced back to China. The Chinese refer to Ganoderma as the 'King of Herbs' and its alternative names are Rei Shi and Ling Zhi. Ganoderma is also effective in preventing tumors, and detoxifies the liver. It has also been said that it is effective in curing heart ailments, insomnia, high blood pressure, diabetes, chronic asthma and bronchitis. So coffee beans infused with Ganoderma extracts produces this highly nutritious and healthy beverage called Ganoderma coffee. Ganoderma lucidum and its proven medical efficacy has been acknowledged and endorsed by the American Herbal Pharmacopoeia. This herb is also known as the Red Mushroom. Ganoderma has been researched extensively for its therapeutic and healing properties. So Ganoderma coffee is perhaps the best thing to have been discovered for coffee connoisseurs all over the world ... ... continue
Effect of Ganoderma on drug-sensitive and multidrug-resistant small-cell lung carcinoma cellsMultidrug resistance is a major problem in small-cell lung cancer (SCLC). Ganoderma lucidum is a widely used herb in traditional Chinese medicine. We tested the effects of Ganoderma on drug-sensitive (H69) and multi-drug resistant (VPA) human SCLC cells. Both cells showed equal cytotoxicity when incubated with extracts of mycelia of 9 species of Ganoderma, including G. lucidum. Cells treated with the IC(50) of cytotoxic Ganoderma and analyzed by flow cytometry-PI staining showed increases in S phase. When compared untreated controls or SCLC cells treated with extracts of non-cytotoxic Ganoderma species, cells treated with extracts of cytotoxic Ganoderma species responded with an induction of apoptosis similar to cells treated with the chemotherapeutic drugs etoposide and doxorubicin ... ... continue Cold Sore Remedie Reishi, also called Ganoderma lucidum is a type of mushroom that has a long history of use in traditional Asian medicine to strengthen the immune system. ... continue Ganoderma lucidum (Fr.) P. Karst enhances activities of heart mitochondrial enzymes and respiratory chain complexes in the aged ratAging is associated with increased oxidative damage at multiple cellular levels, decline in cellular energy production and enhanced free radical status. The effect of the medicinal mushroom, Ganoderma lucidum on the activities of tricarboxylic acid (Krebs) cycle enzymes and mitochondrial complexes I-IV of the electron transport chain in aged rats were investigated. The activity of Krebs cycle enzymes, isocitrate dehydrogenase, alpha-ketoglutarate dehydrogenase, succinate dehydrogenase, and malate dehydrogenase as well as mitochondrial complexes I, II, III, and IV were determined in heart of aged male Wistar rats orally administrated with 70% ethanolic extract (50 and 250 mg/kg) of G. lucidum. DL-alpha-lipoic acid (100 mg/kg) was taken as the positive control ... ... continue Lipid extract from completely sporoderm-broken germinating Ganoderma sinensis spores elicits potent antitumor immune responses in human macrophagesGanoderma sinensis has been used widely in Oriental countries for the prevention and treatment of various diseases including cancer. Previous studies have shown that the lipid extract from Ganoderma exhibits direct cytotoxicity against tumor cells. Here, it is reported that the lipid extract from germinating G. sinensis spores, at lower concentrations that have no direct tumoricidal activity, induce potent antitumor immune responses in human monocytes/macrophages. Upon stimulation with the lipid extract, monocytes/macrophages exhibited markedly increased production of proinflammatory cytokines and surface expression of costimulatory molecules. Conditioned medium from stimulated cells effectively suppressed the growth of tumor cells. Apparently, the lipid extract triggered macrophage activation via a mechanism different from that associated with LPS. Moreover, it was observed that the lipid extract could partially re-establish the antitumor activity of the immunosuppressive tumor-associated macrophages ... ... continue Ganoderma lucidum extract attenuates the proliferation of hepatic stellate cells by blocking the PDGF receptorHepatic fibrosis is an outcome of chronic liver diseases. The activation and proliferation of hepatic stellate cells (HSCs) is a key event in liver injury. The fruiting body of Ganoderma lucidum has long been a popular oriental medicine for treating liver diseases. The aim of this present study was to investigate the antiproliferative effects of the triterpenoid-rich extract (GLT) of G. lucidum in a cell line of rat HSCs (HSC-T6) stimulated with platelet-derived growth factor (PDGF)-BB. DNA synthesis was investigated by bromodeoxyuridine (BrdU) incorporation ... ... continue
Effect of Ganoderma lucidum on the activities of mitochondrial dehydrogenases and complex I and II of electron transport chain in the brain of aged ratsDysfunction of the mitochondrial respiratory chain, being direct intracellular source of reactive oxygen species (ROS), is important in the pathogenesis of number of ageing associated human disorders. Effect of ethanol extract of Ganoderma lucidum on the activities of mitochondrial dehydrogenases; complex I and II of electron transport chain have been evaluated in the aged rat brain. Aged male Wistar rats were administered with ethanol extract of G. lucidum (50 and 250mg/kg, p.o) once daily for 15 days. Similarly DL-alpha-lipoic acid (100mg/kg, p.o) administered group was kept as the reference standard. Young and aged rats administered with water were kept as young and aged control, respectively. ... ... continue Ganoderma - The Health Benefits of GanodermaGanoderma shows promise in reducing cholesterol levels and easing allergy-related inflammation of the airways, according to preliminary evidence from animal-based studies. Here's a look at more of the science behind ganoderma's health-enhancing effects ... Ganoderma is available in capsules and liquid extracts, both of which can be found at health food stores. You can also take ganoderma in tea or coffee form, but beware that the flavor may be bitter. Some people experience dry nose, dry throat, nausea, and gastrointestinal problems (such as nausea) when taking ganoderma. Since the mushroom might interact with certain medications (such as anticoagulants and some chemotherapeutic agents), it's important to tell your physician if you're currently taking or considering the use of ganoderma ... ... continue
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